Formic Acid → HCID 178426443, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 284 using N1,N1,N2-trimethylethane-1,2-diamine and 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid to give a formic acid salt (61 mg, 0.135 mmol, 72.3%) as an off-white solid. MS: 405 (M+H). 1H NMR (400 MHz, DMSO-d6) δ ppm 2.42 (s, 3 H) 2.53-2.70 (m, 4 H) 3.02 (s, 3 H) 3.11-3.80 (m, 6 H) 7.53 (d, J=8.3 Hz, 1 H) 7.58 (s, 1 H) 7.89-7.99 (m, 2 H) 8.10 (br. s., 1 H) 8.50 (m, 2 H).

Provenance & Evidence