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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 579099Generated: October 30, 2026

Pyrrolidine → HCID 178422199, compound

https://huagongshe.com/reaction/579099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantHCID 178422218HCID 178422218—
ProductHCID 178422199HCID 178422199—

Reaction Steps

The title compound was prepared in a manner similar to Example 301 using 6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and pyrrolidine. 1H NMR (500 MHz, DMSO-d6) δ ppm 1.79-1.95 (m, 4 H) 2.33 (d, J=2.44 Hz, 3H) 3.49 (t, J=5.61 Hz, 4 H) 7.42-7.82 (m, 2 H) 7.84-8.76 (m, 4 H). ESI-MS m/z [M+H]+392.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040522B2
Source datasetuspto-grants-2015_05
ORD IDord-46a0f4ca5bc049379a748658c4beee64
Source noteuspto-grants-2015_05