(8aR)-Octahydropyrrolo(1,2-a)pyrazine → HCID 178422209, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 303 using 6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (R)-octahydropyrrolo[1,2-a]pyrazine. 1H NMR (400 MHz, DMSO-d6) δ ppm 2.08 (s, 4 H) 2.33 (d, J=2.53 Hz, 3 H) 2.81-4.24 (m, 9 H) 7.64 (br. s., 1 H) 7.75 (t, J=7.45 Hz, 1 H) 7.95-8.83 (m, 4 H). ESI-MS m/z [M+H]+ 447.3.

Provenance & Evidence