HCID 29892937, compound → HCID 178422214, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 303 using 6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (R)-1-isopropyl-2-methylpiperazine. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.18 (d, J=5.81 Hz, 4H) 1.30 (d, J=6.32 Hz, 5 H) 2.33 (d, J=2.27 Hz, 3 H) 2.85-3.65 (m, 5 H) 3.89 (br. s., 2 H) 4.20-4.83 (m, 1 H) 7.64 (br. s., 1 H) 7.70-7.79 (m, 1 H) 7.93-8.77 (m, 4 H) 9.36-10.10 (m, 1 H). ESI-MS m/z [M+H]+ 463.3.

Provenance & Evidence