HCID 28937399, compound → HCID 178495119, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (R)-4-methoxybutan-2-amine 1H NMR (400 MHz, DMSO-d6) δ ppm 1.19 (d, J=6.82 Hz, 3 H) 1.67-1.77 (m, 1 H) 1.77-1.89 (m, 1 H) 2.44 (s, 3 H) 3.39 (t, J=6.57 Hz, 2 H) 4.05-4.20 (m, 1 H) 7.67 (d, J=8.08 Hz, 1 H) 7.74 (s, 1 H) 7.78 (br. s., 1 H) 8.17 (br. s., 1 H) 8.43 (d, J=7.07 Hz, 3H) 8.87-8.95 (m, 1 H) 12.98-13.34 (m, 1 H); ESI-MS m/z [M+H]+ 406.2.

Provenance & Evidence