HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 28937401, compound → HCID 178495120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 28937401 | HCID 28937401 | — |
| Reactant | HCID 178426451 | HCID 178426451 | — |
| Product | HCID 178495120 | HCID 178495120 | — |
Reaction Steps
The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (S)-4-methoxybutan-2-amine 1H NMR (400 MHz, DMSO-d6) δ ppm 1.19 (d, J=6.82 Hz, 3 H) 1.67-1.77 (m, 1 H) 1.77-1.88 (m, 1 H) 2.44 (s, 3 H) 3.23 (s, 3 H) 3.39 (t, J=6.57 Hz, 2 H) 4.06-4.20 (m, 1 H) 7.67 (d, J=8.08 Hz, 1 H) 7.73 (s, 1 H) 7.78 (br. s., 1 H) 8.17 (br. s., 1 H) 8.43 (d, J=7.33 Hz, 3 H) 8.89-8.95 (m, 1 H) 13.16 (br. s., 1 H); ESI-MS m/z [M+H]+ 406.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040522B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-c733c3f9b49c411e968e7d5463162592 |
| Source note | uspto-grants-2015_05 |