1-Methyl-4-(methylamino)piperidine → HCID 178428091, compound

HRID 579154Notes

Reaction equation

HRID 579154 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[N:11][N:12]([C:15]3[CH:23]=[C:22]([CH3:24])[C:18]([C:19]([OH:21])=O)=[CH:17][N:16]=3)[C:13]=2[OH:14])=[CH:5][CH:4]=1)#[N:2].[CH3:25][NH:26][CH:27]1[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29][CH2:28]1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[N:11][N:12]([C:15]3[CH:23]=[C:22]([CH3:24])[C:18]([C:19]([N:26]([CH3:25])[CH:27]4[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29][CH2:28]4)=[O:21])=[CH:17][N:16]=3)[C:13]=2[OH:14])=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 5663231-Methyl-4-(methylamino)piperidineHCID 178428092HCID 178428092, compound

Product 1

HCID 178428091HCID 178428091, compound

Procedure

The title compound was prepared in a manner similar to Example 412 using 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-4-methylnicotinic acid and N,1-dimethylpiperidin-4-amine. ESI-MS m/z (M+H)+ calc'd for C24H26N6O2, 431.21; found 431.5.

Sources & evidence

ORD record
ord-722fb3a81cc4402c846e3121092a0c27
Source dataset
uspto-grants-2015_05
Patent number
US09040522B2

Reaction notes

Loading…