HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chlorovaleryl chloride → HCID 13656413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chlorovaleryl chloride | HCID 74089 | — |
| Reactant | 6,11-Dihydrodibenzo[b,e]thiepin-11-amine | HCID 12489100 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 13656413 | HCID 13656413 | 93.4% |
Reaction Steps
A mixture of 8.8 g of 11-amino-6,11-dihydrodibenzo[b,e]thiepin, 6.0 g of 5-chlorovaleryl chloride and 100 ml of dioxane is heated with stirring under reflux for 15 hours. The solvent is distilled off under reduced pressure. The residue is recrystallized from ethanol to give 12.5 g of the title compound, m.p. 155°-156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04749703 |
| Source dataset | uspto-grants-1988_06 |
| ORD ID | ord-803d42ff85124d48bb7b648bf79a6341 |
| Source note | uspto-grants-1988_06 |