反应详情

A stirred mixture of 6-(4-aminophenyl)-3(2H)-pyridazinone hydrochloride (1.5 g), 4H-pyran-4-one (0.71 g), and water (20 ml), was heated under reflux for 2 hours. The pH of the hot solution was adjusted to 8 with aqueous ammonia and the mixture was cooled to give the crude product, 1.84 g, m.p. 338°-340° C. Recrystallisation from aqueous ethanol gave the title compound, 1.4 g, m.p. 339°-341° C.

1. temperaturewas heated
2. temperatureunder reflux for 2 hours
3. temperaturethe mixture was cooled
4. customto give the crude product, 1.84 g, m.p. 338°-340° C
5. customRecrystallisation from aqueous ethanol