HRID579842

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID689043

trans-Caffeic acid

C9H8O4

$结构：CN/C(=N\CCSCc1nc[nH]c1C)NC#N$

HCID178484997

未命名化合物

PRODUCTS

生成物

$结构：CN/C(=N\CCSCc1nc[nH]c1C)NC#N.O=C([O-])/C=C/c1ccc(O)c(O)c1$

HCID178485002

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

A mixture of 1.26 g (0.5 cmole) cimetidine and 0.95 g (0.5 cmole) of caffeic acid (97%) were suspended in 12 ml of dichloromethane. The mixture was stirred for 2 hours at room temperature, followed by filtration and washing with dichloromethane. Dry weight: 2.17 g. Quantitative yield. M.p.: 126°-130° C. IR FIG. 1.

WORKUP

后处理

filtrationfollowed by filtration
washwashing with dichloromethane
customDry weight