Ranisen → HCID 178484398, compound

HRID 579846Notes

Reaction equation

HRID 579846 reaction equation
[CH3:1][NH:2][C:3]([NH:8][CH2:9][CH2:10][S:11][CH2:12][C:13]1[O:17][C:16]([CH2:18][N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=1)=[CH:4][N+:5]([O-:7])=[O:6].[C:22]([OH:34])(=[O:33])/[CH:23]=[CH:24]/[C:25]1[CH:32]=[CH:31][C:29]([OH:30])=[C:27]([OH:28])[CH:26]=1>ClCCl>[CH3:1][NH:2][C:3]([NH:8][CH2:9][CH2:10][S:11][CH2:12][C:13]1[O:17][C:16]([CH2:18][N:19]([CH3:20])[CH3:21])=[CH:15][CH:14]=1)=[CH:4][N+:5]([O-:7])=[O:6].[C:22]([O-:34])(=[O:33])/[CH:23]=[CH:24]/[C:25]1[CH:32]=[CH:31][C:29]([OH:30])=[C:27]([OH:28])[CH:26]=1

Participants

4

Reactant 2

HCID 5039RanisenHCID 689043Caffeic Acid

Product 1

HCID 178484398HCID 178484398, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 1.57 g (0.5 cmole) of ranitidine and 0.95 g (0.5 cmole) of caffeic acid were suspended in dichloromethane (15 ml). The mixture was stirred for 2 hours 30 minutes at room temperature, was filtered, washed with dichloromethane. Dry weight 2.4 g. Quantitative yield.

Workup

  1. filtrationwas filtered
  2. washwashed with dichloromethane
  3. customDry weight 2.4 g

Sources & evidence

ORD record
ord-b96f176e538e4730bfed347fd0b40ac8
Source dataset
uspto-grants-1988_06
Patent number
US04749790

Reaction notes

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