Dimethyl Sulfate → 4-Methylbiphenyl

Participants

Reaction Conditions

Reaction Steps

In 1.5 l of a 1.5N aqueous sodium hydroxide solution was dissolved 170 g of p-hydroxybiphenyl, and 254 g of dimethyl sulfate was dropped into the content while the temperature of the content was maintained at 55° C. Reaction was carried out with stirring at 70° C. for 30 minutes. The reaction product was recovered by filtration and dried under a reduced pressure. Recrystallization of the product from ethanol yielded 150 g of 4-methylbiphenyl (melting point=75°-76° C.).

Provenance & Evidence