Thionyl Chloride → 4'-Decyloxybiphenyl-4-carboxylic acid chloride

Participants

Reaction Steps

This ester was dissolved in 50 ml of a 10% by weight solution of sodium hydroxide in a methanol/water mixed solvent (1/1 volume ratio). The solution was refluxed for 6 hours and, subsequently, the reaction mixture was dropped in an ice-cooled aqueous hydrochloric acid solution to form a white powdery precipitate. The precipitate was recovered by filtration, washed with water and then dried to obtain 2.0 g of 4-n-decyloxybiphenyl-4'-carboxylic acid. 2.0 g of the 4-n-decyloxybiphenyl-4'-carboxylic acid was incorporated with 10 ml of thionyl chloride, and the mixture was refluxed for 2 hours. Unreacted thionyl chloride was removed under a reduced pressure to obtain 2.2 g of 4-n-decyloxybiphenyl-4'-carboxylic acid chloride.

Provenance & Evidence