Ammonia → 3-(1,4-Diazepan-1-yl)propan-1-ol

HRID 580031Notes

Reaction equation

[C:1]([CH2:3][N:4]([CH2:9][CH2:10][C:11]#[N:12])[CH2:5][CH2:6][CH2:7][OH:8])#N.N>>[OH:8][CH2:7][CH2:6][CH2:5][N:4]1[CH2:9][CH2:10][CH2:11][NH:12][CH2:1][CH2:3]1

Participants

Reactant 2

HCID 222Ammonia

HCID 13556941HCID 13556941, compound

Product 1

HCID 135569423-(1,4-Diazepan-1-yl)propan-1-ol

Procedure

hydrogenating the cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amine in the presence of a hydrogenation catalyst and ammonia to form 1-(3-hydroxy-propyl)-1,4-diazepane;

Sources & evidence

ORD record: ord-5d97c1bb227940b79ebb33c42592f4df
Source dataset: uspto-grants-1988_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04751298

Reaction notes

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