HCID 6626195, compound → HCID 70415764, compound

Participants

Reaction Steps

Following the procedure of Example 1 Part B, but using 1.19 g of 7-methoxy-3-benzofuranacetic acid and 0.53 g of n-propylamide in place of cyclopropylmethylamine, and heating to 48° for 19 hours, there was obtained 1.07 g (96%) of N-(n-propyl)-7-methoxy-3-benzofuranacetamide as a solid. NMR spectrum (200 mHz in CDCl3): δ0.8 (t, J=7 Hz, 3H), 1.4 (m, 2H), 3.15 (q, J=6 Hz, 2H), 3.63 (s, 2H), 4.0 (s, 3H), 5.5-5.7 (broad s, 1H), 6.85 (d/d, J=7.0/0.5 Hz, 1H) 7.1-7.3 (m, 2H) and 7.61 (s, 1H).

Provenance & Evidence