HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobenzaldehyde → MS-1845
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobenzaldehyde | HCID 11101 | — |
| Reactant | Nitrobenzylbromide | HCID 11356361 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Product | MS-1845 | HCID 309824 | — |
Reaction Steps
Nitrobenzylbromide is derived from nitrobenzaldehyde, which is then reacted with potassium phthalimide to obtain N-(m-nitrobenzyl)-phthalimide, and m-aminobenzylamine is produced with an yield of about 20% by a two-step reduction reaction (N. Kornblum et al, J. Am. Chem. Soc., 71, 2137 (1949)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04751328 |
| Source dataset | uspto-grants-1988_06 |
| ORD ID | ord-860aebe20ad1412ea9c59b5118ccfe00 |
| Source note | uspto-grants-1988_06 |