Benzeneacetic acid, 4-hydroxy-, methyl ester → Methyl 4-[4-(2,3,4,5-tetramethoxy-6-methylphenyl)-2-methyl-2-butenyloxy]phenylacetate

HRID 580238Notes

Reaction equation

HRID 580238 reaction equation
[CH3:1][O:2][C:3]1[C:8]([CH2:9][CH:10]=[C:11]([CH3:14])[CH2:12]Cl)=[C:7]([CH3:15])[C:6]([O:16][CH3:17])=[C:5]([O:18][CH3:19])[C:4]=1[O:20][CH3:21].[OH:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:25][CH:24]=1>>[CH3:1][O:2][C:3]1[C:4]([O:20][CH3:21])=[C:5]([O:18][CH3:19])[C:6]([O:16][CH3:17])=[C:7]([CH3:15])[C:8]=1[CH2:9][CH:10]=[C:11]([CH3:14])[CH2:12][O:22][C:23]1[CH:24]=[CH:25][C:26]([CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:27][CH:28]=1.[CH3:1][O:2][C:3]1[C:4]([O:20][CH3:21])=[C:5]([O:18][CH3:19])[C:6]([O:16][CH3:17])=[C:7]([CH3:15])[C:8]=1[CH2:9][CH:10]=[C:11]([CH3:14])[CH2:12][O:22][C:23]1[CH:24]=[CH:25][C:26]([CH2:29][C:30]([OH:32])=[O:31])=[CH:27][CH:28]=1

Participants

4

Reactant 2

HCID 518900Benzeneacetic acid, 4-hydroxy-, methyl esterHCID 538691681,2,3,4-Tetramethoxy-5-methyl-6-(4-chloro-3-methyl-2-butenyl)benzene

Product 2

HCID 86740178Methyl 4-[4-(2,3,4,5-tetramethoxy-6-methylphenyl)-2-methyl-2-butenyloxy]phenylacetateHCID 867401794-[4-(2,3,4,5-Tetramethoxy-6-methylphenyl)-2-methyl-2-butenyloxy]phenylacetic acid

Procedure

Using 1,2,3,4-tetramethoxy-5-methyl-6-(4-chloro-3-methyl-2-butenyl)benzene and methyl p-hydroxyphenylacetate and following the procedure described above, there were obtained methyl 4-[4-(2,3,4,5-tetramethoxy-6-methylphenyl)-2-methyl-2-butenyloxy]phenylacetate (Compound 15) and 4-[4-(2,3,4,5-tetramethoxy-6-methylpheny)-2-methyl-2-butenyloxy]phenylacetic acid (Compound 16).

Sources & evidence

ORD record
ord-833eba5b956341c198618cae2a09f50d
Source dataset
uspto-grants-1988_06
Patent number
US04751303

Reaction notes

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