Chlorine → HCID 13921223, compound

HRID 580265Notes

Reaction equation

HRID 580265 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([O:9][S:10]([CH3:13])(=[O:12])=[O:11])=[CH:4][C:3]=1[N:14]1[C:18]([CH3:19])=[CH:17][C:16]([C:20]([F:23])([F:22])[F:21])=[N:15]1.[Cl:24]Cl>C(Cl)(Cl)Cl>[F:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([O:9][S:10]([CH3:13])(=[O:11])=[O:12])=[CH:4][C:3]=1[N:14]1[C:18]([CH3:19])=[C:17]([Cl:24])[C:16]([C:20]([F:21])([F:22])[F:23])=[N:15]1

Participants

4

Reactant 2

HCID 24526ChlorineHCID 13921151HCID 13921151, compound

Product 1

HCID 13921223HCID 13921223, compoundYield 98.7%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Into a solution of 1-(2-fluoro-4-chloro-5-methylsulfonyloxyphenyl)-3-trifluoromethyl-5-methylpyrazole (37.3 g) in chloroform (200 ml) was introduced chlorine gas (7.1 g) at 60° C. for 20 minutes. Removal of the solvent from the reaction solution by distillation in vacuo gave the titled compound (40.2 g) as a pale yellow oil which soon crystallized on standing at room temperature. Recrystallization from a mixture of n-hexane/benzene yielded a white crystalline solid. m.p. 72°-74.5° C.

Workup

  1. customRemoval of the solvent from the reaction solution
  2. distillationby distillation in vacuo

Sources & evidence

ORD record
ord-fea4ab295bde4be693f793f6fdd9da75
Source dataset
uspto-grants-1988_06
Patent number
US04752326

Reaction notes

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