反应详情

N-benzoyl-D,L-isoleucyl-L-proline benzyl ester (1.1 g) was dissolved in methanol (15 ml), and 10% palladium-carbon (120 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a colourless sticky matter (1.04 g, 99%), which was directly used for the next reaction.

1. customto react at room temperature for 3 h
2. filtrationfiltered
3. concentrationconcentrated under reduced pressure
4. customto remove the solvent
5. customto give a colourless sticky matter (1.04 g, 99%), which
6. customwas directly used for the next reaction