HCID 86700990, compound → N-benzenesulfonyl-D-leucyl-(S)-azetidine-2-carboxylic acid

Participants

Reaction Steps

N-benzenesulfonyl-D-leucyl-(S)-azetidine-2-carboxylic acid benzyl ester (667 mg) was dissolved in methanol (10 ml), and 10% palladium-carbon (80 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a white foam-like solid (520 mg, 99%), which was directly used for the next reaction.

Provenance & Evidence