HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580438Generated: October 30, 2026
8-Amino-2-naphthalenol → n-(7-Hydroxynaphthalen-1-yl)formamide
https://huagongshe.com/reaction/580438
Participants
| Role | Name | HCID | Charge |
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| Reactant | 8-Amino-2-naphthalenol | HCID 8358 | — |
| Reactant | Acetic anhydride formic acid | HCID 19869020 | — |
| Product | n-(7-Hydroxynaphthalen-1-yl)formamide | HCID 244439 | — |
Reaction Steps
Ten grams of 8-amino-2-naphthol were added to a mixture of acetic anhydride/formic acid (40 mL:20 mL). The mixture was warmed at 50° C. for one hour and then quenched on ice. After stirring for some time, the product solidified and was filtered off. Recrystallization from ethanol gave 6 g of 8-formamido-2-naphthol melting at 203°-205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04753922 |
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| Source dataset | uspto-grants-1988_06 |
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| ORD ID | ord-402682e39859488ca790276b1fbdf26b |
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| Source note | uspto-grants-1988_06 |
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