関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Isatoic Anhydride | HCID 8359 | — |
| 反応物 | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2-amino-N-(3-imidazol-1-ylpropyl)benzamide | HCID 2798335 | — |
反応手順
A mixture of 2.39 of isatoic anhydride, 2.50 g of 1H-imidazol-1-propanamine and 30 ml of toluene was heated at 90° C. for 45 minutes and cooled. The toluene layer was decanted and the residue was dissolved in methylene chloride, washed with dilute sodium hydroxide solution, water and dried over magnesium sulfate. The organic layer was concentrated to obtain the desired product, mp 107°-110° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04753944 |
|---|
| 出典データセット | uspto-grants-1988_06 |
|---|
| ORD ID | ord-15711c1fa58d45dcba4e9922f5a06c38 |
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| 出典メモ | uspto-grants-1988_06 |
|---|
