5-Chloroisatoic anhydride → 2-Amino-5-chloro-N-[3-(1H-imidazol-1-yl)propyl]benzamide

HRID 580468Notes

Reaction equation

HRID 580468 reaction equation
[Cl:1][C:2]1[CH:13]=[C:6]2[C:7]([O:9]C(=O)[NH:11][C:5]2=[CH:4][CH:3]=1)=O.[N:14]1([CH2:19][CH2:20][CH2:21][NH2:22])[CH:18]=[CH:17][N:16]=[CH:15]1>>[NH2:11][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:13][C:6]=1[C:7]([NH:22][CH2:21][CH2:20][CH2:19][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1)=[O:9]

Participants

3

Reactant 2

HCID 784805-Chloroisatoic anhydrideHCID 787361H-Imidazole-1-propanamine

Product 1

HCID 135889602-Amino-5-chloro-N-[3-(1H-imidazol-1-yl)propyl]benzamide

Procedure

When 5-chloroisatoic anhydride was reacted with 1H-imidazole-1-propanamine by the procedure of Example 11, the above compound, mp 155°-157° C., was obtained.

Workup

  1. customthe above compound, mp 155°-157° C., was obtained

Sources & evidence

ORD record
ord-7cd7f5d59fd246729a78d87fcf3dd12c
Source dataset
uspto-grants-1988_06
Patent number
US04753944

Reaction notes

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