HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580496Generated: October 31, 2026
3,4-Dichlorophenol → HCID 20134004, compound
https://huagongshe.com/reaction/580496
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dichlorophenol | HCID 7258 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 7-Chloro-1,8-naphthyridin-2-amine | HCID 85199 | — |
| Product | HCID 20134004 | HCID 20134004 | 58.8% |
Reaction Steps
The procedure is similar to that described in Example 24, but starting with 2-amino-7-chloro-1,8-naphthyridine (17.95 g), 3,4-dichlorophenol (65.2 g) and potassium hydroxide pellets (85% pure; 13.2 g), heating to 125° C. for 22 hours. On recrystallization in acetonitrile (1500 cc) of the crude product obtained, 2-amino-7-(3,4-dichlorophenoxy)-1,8-naphthyridine (18 g), m.p. 206° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04753941 |
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| Source dataset | uspto-grants-1988_06 |
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| ORD ID | ord-d9f6204c064147c8b79f816976cf8536 |
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| Source note | uspto-grants-1988_06 |
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