Ethylamine → HCID 13958323, compound

HRID 580525Notes

Reaction equation

HRID 580525 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH2:15]([NH2:17])[CH3:16]>C(O)C>[CH2:15]([NH:17][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])[CH3:16]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 112758084-Chloro-3-nitroquinoline

Product 1

HCID 13958323HCID 13958323, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a stirred suspension of 1.40 g of 4-chloro-3-nitroquinoline in 30 ml of dry ethanol is introduced excess amount of gaseous ethylamine at room temperature for 3 hours. Treatment of the reaction mixture as in Example 98 yielded 1.41 g (97%) of 4-ethylamino-3-nitroquinoline. Recrystallization from the ethyl acetate-n-hexane affords yellow crystals melting at 151°-152° C.

Sources & evidence

ORD record
ord-c58f218530dc4938b08147b1148b294a
Source dataset
uspto-grants-1988_06
Patent number
US04753951

Reaction notes

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