HCID 13958323, compound → HCID 13958352, compound

HRID 580526Notes

Reaction equation

HRID 580526 reaction equation
[CH2:1]([NH:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]=[CH:6][C:5]=1[N+:14]([O-])=O)[CH3:2]>C(O)C.[Pd]>[NH2:14][C:5]1[CH:6]=[N:7][C:8]2[C:13]([C:4]=1[NH:3][CH2:1][CH3:2])=[CH:12][CH:11]=[CH:10][CH:9]=2

Participants

4

Reactant 1

HCID 13958323HCID 13958323, compound

Product 1

HCID 13958352HCID 13958352, compoundYield 82.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A suspension of 1.34 g of 4-ethylamino-3-nitroquinoline in 40 ml of ethanol is hydrogenated in the presence of 10% palladium on carbon according to the procedure of Referential Example 1, followed by purification to give 0.95 g (82%) of 3-amino-4-ethylaminoquinoline A16 as an oil.

Workup

  1. customfollowed by purification

Sources & evidence

ORD record
ord-5888b8d32a004afaa046a2d777f07737
Source dataset
uspto-grants-1988_06
Patent number
US04753951

Reaction notes

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