反应详情

A suspension of 1-benzyl-trans-3-t-butoxycarbonylamino-4-methylpyrrolidine (4.8 g) and 10% palladium-on-charcoal (1.8 g) in ethanol (40 ml) was shaken with hydrogen were absorbed under elevated pressure (100 kg/cm2) at 50°-70° C. for 6.5 hours. The catalyst was removed by filtration and the filtrate was evaporated to give the title compound (3.09 g) as brown oil. This oil was gradually solidified at room temperature.

1. customwere absorbed under elevated pressure (100 kg/cm2) at 50°-70° C. for 6.5 hours
2. customThe catalyst was removed by filtration
3. customthe filtrate was evaporated