Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Difluorotoluene → 2-Chloro-1-fluoro-3-methylbenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Difluorotoluene | HCID 2733400 | — |
| 반응물 | 3-Chloro-4-fluorotoluene | HCID 2736589 | — |
| 반응물 | 2,3-Difluorotoluene | HCID 2774228 | — |
| 반응물 | 1,1,2-Trifluoro-2-chloro-3-methyl-3-vinylcyclobutane | HCID 2777090 | — |
| 반응물 | HCID 20134583 | HCID 20134583 | — |
| 생성물 | 2-Chloro-1-fluoro-3-methylbenzene | HCID 14227794 | 88% |
반응 단계
The general procedure was followed using a mixture of 1-(2-propenyl)-2-chloro-2,3,3-trifluorocyclobutane and 1-methyl-1-vinyl-2-chloro-2,3,3-trifluorocyclobutane as the liquid feed at a flow rate of 1 ml/hr. Nitrogen gas was used as the inert carrier. The reactor was charged with 3 g of AL-0104 (tableted activated alumina containing 99% Al2O3). At 400° C. the yield of the produced aromatic products was 12% combined yield of 1-methyl-2,3-difluorobenzene and 1-methyl-3,4-difluorobenzene and a combined yield of 88% of 1-methyl-2-chloro-3-fluorobenzene and 1-methyl-3-chloro-4-fluorobenzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04754084 |
| 출처 데이터셋 | uspto-grants-1988_06 |
| ORD ID | ord-7899f866248c4a989f207edd7a3c5df7 |
| 출처 메모 | uspto-grants-1988_06 |