HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580883Generated: October 29, 2026
3-Chloroaniline → HCID 11629788, compound
https://huagongshe.com/reaction/580883
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 11629788 | HCID 11629788 | — |
Reaction Steps
To a solution of 3-chloroaniline and potassium carbonate (3 equiv.) in DMF is added methylbromoacetate (1.1 equiv.), and the reaction is stirred at 60° C. After complete reaction, the solution is poured into EtOAc and washed with water, sat. aq. NaHCO3 soln., and brine. The solution is dried (Na2SO4), filtered, and concentrated in vacuo. The resulting material is purified by silica gel chromatography to provide the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05919785 |
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| Source dataset | uspto-grants-1999_07 |
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| ORD ID | ord-a725d08ce0c04d57bccbf93f0443fb94 |
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| Source note | uspto-grants-1999_07 |
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