Thionyl Chloride → HCID 86754157, compound

Participants

Reaction Steps

2.38 g (10 mmoles) of N-(benzyloxy)nicotinamide (Beilstein 22/V, page 120) are boiled under reflux in 20 ml of thionyl chloride for 2 hours. After distilling off the excess thionyl chloride, the residue is crystallized from isopropanol to give 1.75 g (62%) of the desired product, the physical characteristics of which are identical to those of the product prepared by method A).

Provenance & Evidence