HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 7-Oxa-3-azabicyclo[4.1.0]heptan-3-yl(phenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 3,6-dihydro-2H-pyridin-1-yl(phenyl)methanone | HCID 570037 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 7-Oxa-3-azabicyclo[4.1.0]heptan-3-yl(phenyl)methanone | HCID 332197 | — |
Reaction Steps
A solution of metachloroperbenzoic acid (12 mmole) in methylene chloride is added dropwise to a solution of 39 at 4 C. The reaction mixture is allowed to stir overnight at room temperature. It is made basic and then extracted with methylene chloride. Following work-up and flash chromatography affords 40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05919797 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-38d96c7a65cc4d679f4c6a336398b03f |
| Source note | uspto-grants-1999_07 |