Potassium Hydroxide → HCID 67625173, compound

HRID 580927Notes

Reaction equation

HRID 580927 reaction equation
[C:1]1([C:7]2[N:8]=[C:9]3[N:13]([C:14]=2[CH:15]=O)[C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]=2[S:10]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C[N:22]([C:24](=[O:31])[CH:25]1[CH2:30][CH2:29][CH2:28][NH:27][CH2:26]1)[NH2:23].[OH-].[K+]>CO>[C:1]1([C:7]2[N:8]=[C:9]3[N:13]([C:14]=2[CH:15]=[N:23][NH:22][C:24]([C:25]2[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=2)=[O:31])[C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]=2[S:10]3)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 2760366HCID 2760366, compoundHCID 67575741HCID 67575741, compound

Product 1

HCID 67625173HCID 67625173, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.28 g of 2-phenyl-3-formylimidazo[2,1-b]benzothiazole, 0.15 g of N-methylnipecotohydrazide, and 0.1 g of potassium hydroxide were heated and stirred in 20 ml of methanol at 90° C. for 6 hours. After cooling, the desired substance was obtained in an amount of 0.27 g (yield of 68.0%).

Workup

  1. temperatureAfter cooling
  2. customthe desired substance was obtained in an amount of 0.27 g (yield of 68.0%)

Sources & evidence

ORD record
ord-505c13afc3fc45839c3ce7f5ee716240
Source dataset
uspto-grants-1999_07
Patent number
US05919799

Reaction notes

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