2-(4-Hydroxyphenyl)propionate → Methyl 2-methyl-3-(3-allyl-4-hydroxyphenyl)propionate

Participants

Role	Name	HCID	Charge
Reactant	2-(4-Hydroxyphenyl)propionate	HCID 9543338	—
Reactant	Ethyl 3-{4-[(prop-2-en-1-yl)oxy]phenyl}propanoate	HCID 19348971	—
Reactant	Methyl 2-methyl-3-(4-allyloxyphenyl)propionate	HCID 53880704	—
Reactant	Ethyl 3-[4-hydroxy-3-(prop-2-EN-1-YL)phenyl]propanoate	HCID 54533632	—
Product	Methyl 2-methyl-3-(3-allyl-4-hydroxyphenyl)propionate	HCID 54342166	—

Reaction Steps

Methyl 2-methyl-3-(4-allyloxyphenyl)propionate m/z 235(M+H) was prepared from methyl 2-methyl-3-(4-hydroxyphenylpropionate using the method described in Example 1 for the preparation of ethyl 3-(4-allyloxyphenyl)propionate. Methyl 2-methyl-3-(3-allyl-4-hydroxyphenyl)propionate was prepared from methyl 2-methyl-3-(4-allyloxyphenyl)propionate using the method described in Example 1 for the preparation of ethyl 3-(3-allyl-4-hydroxyphenyl)propionate. The product was isolated as an orange oil; NMR(CDCl3): 1.13(3H,d), 2.40-2.73(2H,m), 2.92(1H,q), 3.37(2H,d), 3.63(3H,s), 4.91(1H,s), 5.03-5.18(2H,m), 5.89-6.10(1H,m), 6.70(1H,m) and 6.91(2H,m); m/z 235(M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05919793
Source dataset	uspto-grants-1999_07
ORD ID	ord-9a35154a4fb34ed2adcd1e7f278446f1
Source note	uspto-grants-1999_07