HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 13340573, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Iodophenylacetic acid | HCID 137214 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13340573 | HCID 13340573 | — |
Reaction Steps
Thionyl chloride (39.53) and DMF (2 drops) were added to a solution of 4-iodophenylacetic acid (26.2 g), in dichloromethane (150 ml). The reaction mixture was stirred at ambient temperature for 18 hours and the solvent removed by evaporation to give 4-iodophenylacetyl chloride as an oil (23 g) which was purified by vacuum distillation; b.p. 118-119° C. (0.35 mmMg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05919793 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-17579de340d84bff8ef4873a7016403c |
| Source note | uspto-grants-1999_07 |