Water → HCID 53775860, compound

Participants

Reaction Conditions

Reaction Steps

1.05 g (3.8 mmol) of 2-(4-chlorobenzyl)-6-hydroxy-benzothiazole and 0.67 g (7.6 mmol) of ethylene carbonate are dissolved in 20 ml of dimethylformamide and after the addition of 2.1 g (15.2 mmol) of potassium carbonate the mixture is stirred for 2 hours at 120° C. It is then added to water and extracted with ethyl acetate. After the extracts have been evaporated down the residue is purified by column chromatography on silica gel (eluant: ethyl acetate). Yield: 1.6 g (69% of theory).

Provenance & Evidence