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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 581247Generated: October 26, 2026

Isovaleryl chloride → 5-(N-[3-methylbutanoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

https://huagongshe.com/reaction/581247

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsovaleryl chlorideHCID 66054—
Reactant3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamineHCID 10220230—
Product5-(N-[3-methylbutanoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridineHCID 1960149260%

Reaction Steps

Beginning with 0.010 gm (0.044 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.048 mMol 3-methylbutanoyl chloride, 0.008 gm (60%) of the title compound were prepared essentially by the procedure described in Example 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05919936
Source datasetuspto-grants-1999_07
ORD IDord-6e96386c2ce344a4b33b980d2f6cb855
Source noteuspto-grants-1999_07