2-Fluoro-4-(trifluoromethyl)benzoyl chloride → 5-(N-[2-fluoro-4-trifluoromethylbenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	2-Fluoro-4-(trifluoromethyl)benzoyl chloride	HCID 145580	—
Reactant	3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine	HCID 10220230	—
Product	5-(N-[2-fluoro-4-trifluoromethylbenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine	HCID 19601587	—

Reaction Steps

Beginning with 0.010 gm (0.044 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.012 mL (0.053 mMol) 2-fluoro-4-trifluoromethylbenzoyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05919936
Source dataset	uspto-grants-1999_07
ORD ID	ord-d5d3e56967cc4b7b95692f72813689c4
Source note	uspto-grants-1999_07