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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 581313Generated: October 26, 2026

4-Fluorobenzoyl chloride → N-[3-(1-Ethyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-4-fluoro-benzamide

https://huagongshe.com/reaction/581313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
Reactant5-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridineHCID 11770686—
ProductN-[3-(1-Ethyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-4-fluoro-benzamideHCID 11122117—

Reaction Steps

Beginning with 0.015 gm (0.061 mMol) 5-amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.009 mL (0.080 mMol) 4-fluorobenzoyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05919936
Source datasetuspto-grants-1999_07
ORD IDord-29e8f20259734154b9dd78ab642a70d3
Source noteuspto-grants-1999_07