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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 581406Generated: October 30, 2026

Methanol → HCID 9955004, compound

https://huagongshe.com/reaction/581406

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodiumHCID 5360545—
ReactantHCID 10503986HCID 10503986—
SolventSodium HydroxideHCID 14798—
ProductHCID 9955004HCID 995500443.4%

Reaction Steps

Using the procedure described in Example 2, Part E, 956 mg (2.1 mmol) of [[3-(2-amino-1,2-dioxoethyl)-1-([1,1'-biphenyl]-3-ylmethyl)-2-methyl-1H-indol-4-yl]oxy]acetic acid methyl ester was hydrolyzed in 10 mL of 1N NaOH and 20 mL of MeOH to give 403 mg (41% yield) of [[3-(2-amino-1,2-dioxoethyl)-1-([1,1'-biphenyl]-3-ylmethyl)-2-methyl-1H-indol-4-yl]oxy]acetic acid, sodium salt, mp, >265° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05919943
Source datasetuspto-grants-1999_07
ORD IDord-455844dee4dd46e5bd558afe2c05bf4c
Source noteuspto-grants-1999_07