Ammonium Acetate → HCID 54429941, compound

Participants

Reaction Conditions

Reaction Steps

1.25 g of 2-ethoxalylamino-1-indanone are added rapidly to a solution of 12.5 g of ammonium acetate in 50 ml of acetic acid brought to reflux under nitrogen. After 18 hours of reflux, the reaction medium is cooled to a temperature in the region of 20° C. The precipitate formed is filtered off, washed copiously with water and dried under a partial vacuum (1 mm Hg; 0.13 kPa) at 50° C. 0.77 g of 1,4-dihydro-5H-indeno[1,2-b]pyrazine-2,3-dione are thereby obtained in the form of a green powder, the melting point of which is above 260° C. (analysis C11H8N2O2 ; 1.18 H2O; % calculated C: 66.00; H: 4.03; N: 13.99; % found C: 65.7; H: 3.9; N: 13.9).

Provenance & Evidence