Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 581801Generated: October 30, 2026

Hydrogen chloride-ethyl acetate → HCID 70180684, compound

https://huagongshe.com/reaction/581801

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ReactantHCID 53846273HCID 53846273—
ProductHCID 70180684HCID 70180684—

Reaction Steps

8-[2,6-Dichloro-3-[N-[4-[(N-tert-butoxycarbonyl-L-prolyl)amino]cinnamoylglycyl]-N-methylamino]benzyloxy]-2-methylquinoline (170 mg) was treated with 4M hydrogen chloride-ethyl acetate (2 ml) at ambient temperature for 30 minutes. The reaction mixture was concentrated to give 8-[2,6-dichloro-3-[N-[4-(L-prolylamino)cinnamoylglycyl]-N-methylamino]benzyloxy]-2-methylquinoline dihydrochloride (152 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05922711
Source datasetuspto-grants-1999_07
ORD IDord-468c5f206370487c9c78cbefaf57a9d4
Source noteuspto-grants-1999_07