4-(2-Chlorophenyl)piperidine-4-carbonitrile → 4-o-Tolylpiperidine-4-carbonitrile

HRID 581802Notes

Reaction equation

HRID 581802 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([C:14]#[N:15])[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.Cl[C:17]1C=CC=CC=1C1(C(OC)=O)CCNCC1>>[C:14]([C:8]1([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:17])[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)#[N:15]

Participants

3

Reactant 2

HCID 154079254-(2-Chlorophenyl)piperidine-4-carbonitrileHCID 442140454-(2-Chlorophenyl)-4-(methoxycarbonyl)piperidine

Product 1

HCID 101765704-o-Tolylpiperidine-4-carbonitrile

Procedure

4-(2-chlorophenyl)-4-cyanopiperidine or 4-(2-chlorophenyl)-4-(methoxycarbonyl)piperidine

Sources & evidence

ORD record
ord-f96c095369de47eeb1acbf0caebea268
Source dataset
uspto-grants-1999_07
Patent number
US05922722

Reaction notes

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