HCID 54073381, compound → HCID 69977651, compound

HRID 581856Notes

Reaction equation

HRID 581856 reaction equation
[CH:1]([C:4]1[C:5](=[O:18])[NH:6][C:7](=[O:17])[NH:8][C:9]=1[S:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([CH3:3])[CH3:2].[C:19]([CH:23]1[CH2:27][C:26](CBr)=[C:25]([CH2:30][O:31][SiH](C)C)[CH2:24]1)(C)(C)C>>[OH:31][CH2:30][CH:25]1[CH2:24][C:23]([CH2:19][N:8]2[C:9]([S:10][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:18])[NH:6][C:7]2=[O:17])=[CH:27][CH2:26]1

Participants

3

Reactant 2

HCID 54073381HCID 54073381, compoundHCID 131721303HCID 131721303, compound

Product 1

HCID 69977651HCID 69977651, compoundYield 29.5%

Procedure

5-Isopropyl-6-phenylthio-2,4-pyrimidinedione and [(4-t-butyldimethylsilyl-oxymethylcyclopent-1-en-1-yl)methyl bromide were reacted by the same way with the example 6 to obtain the titled compound (67 mg)

Sources & evidence

ORD record
ord-ab6855674e4e4e08bb008921a3b6e8b1
Source dataset
uspto-grants-1999_07
Patent number
US05922727

Reaction notes

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