HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione → 1-[(5-Hydroxymethylcyclopent-1-en-1-yl)methyl]-5-Isopropyl-6-(3,5-dimethyl-phenylthio)-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione | HCID 10493727 | — |
| Reactant | (5-t-Butyldimethylsilyloxymethylcyclopent-1-en-1-yl)methyl bromide | HCID 53795506 | — |
| Product | 1-[(5-Hydroxymethylcyclopent-1-en-1-yl)methyl]-5-Isopropyl-6-(3,5-dimethyl-phenylthio)-2,4-pyrimidinedione | HCID 53996428 | 37.6% |
Reaction Steps
5-Isopropyl-6-(3,5-dimethylphenylthio)-2,4-pyrimidinedione and (5-t-butyldimethylsilyloxymethylcyclopent-1-en-1-yl)methyl bromide were reacted by the same with the example 10 to obtain the titled compound (83 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922727 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-16314345f0474942bdcc4c56cef5c33d |
| Source note | uspto-grants-1999_07 |