HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione → 1-{[3,4-Di(hydroxymethyl)cyclopent-1-en-1-yl]methyl}-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione | HCID 22256582 | — |
| Reactant | [3,4-Di(t-butyldimethylsilyloxymethyl)cyclopent-1-en-1-yl]methyl bromide | HCID 54350482 | — |
| Product | 1-{[3,4-Di(hydroxymethyl)cyclopent-1-en-1-yl]methyl}-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione | HCID 69977807 | 26.3% |
Reaction Steps
5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and [3,4-di(t-butyldimethylsilyloxymethyl)cyclopent-1-en-1-yl]methyl bromide were reacted by the same method with example 28 to obtain the titled compound (74 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922727 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-0876341c625343e3aca665566e713242 |
| Source note | uspto-grants-1999_07 |