HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-Acetyl 3-(1-imidazolyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-(1H-imidazol-1-yl)aniline | HCID 321225 | — |
| Product | N-Acetyl 3-(1-imidazolyl)aniline | HCID 47215507 | 85% |
Reaction Steps
2d (5.88 g, 37 mmol) is stirred in acetic anhydride (30 ml) at ambient temperature for 1 hour. The mixture is poured into ice-water and rendered alkaline by addition of aqueous sodium hydroxide (12M). The product is filtered off, washed with water and dried to yield 2e (6.34 g, 85%). Mp 181-183° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922725 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-5e635deb5a8f4edfb276a285c134a538 |
| Source note | uspto-grants-1999_07 |