HCID 54126803, compound → HCID 11324445, compound

HRID 581899Notes

Reaction equation

HRID 581899 reaction equation
[C:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13](I)[CH:12]=3)[CH:9]=[N:10][C:6]=2[CH:5]=1)(=[O:3])[CH3:2].C(C1C=CC2N=[C:28]([C:30]3[CH:35]=[CH:34][CH:33]=C(Br)C=3)[NH:29]C=2C=1)(=O)C>>[C:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13]([C:34]4[CH:33]=[N:29][CH:28]=[CH:30][CH:35]=4)[CH:12]=3)[CH:9]=[N:10][C:6]=2[CH:5]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 54126803HCID 54126803, compoundHCID 54142306HCID 54142306, compound

Product 1

HCID 11324445HCID 11324445, compound

Procedure

5-Acetyl-1-(3-iodophenyl)benzimidazole in mixture with 5-acetyl-(3-bromophenyl)benzimidazole (36) was prepared analogously from 35 (Example 4). Yield: ~91% (2 steps from 34).

Sources & evidence

ORD record
ord-ad7a9d517a3f4d868b01be64493044e8
Source dataset
uspto-grants-1999_07
Patent number
US05922725

Reaction notes

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