Formic Acid → HCID 54221613, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (60) (3.0 g, 10 mmol) and HCO2H (20 ml) was stirred at 110° C. for 1 hr. The mixture was concentrated in vacuo. The residue was partitioned between a 5% aqueous NaHCO3 solution and CH2Cl2. The organic phase was dried over MgSO4, and the solvent was removed by evaporation. The residue was triturated with ethyl acetate to afford crystalline (61) (2.6g, 85%).

Provenance & Evidence