1-Fluoro-4-iodo-2-nitrobenzene → HCID 67482348, compound

HRID 581935Notes

Reaction equation

HRID 581935 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([I:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[NH2:12][C:13]1[N:18]=[CH:17][C:16]([C:19]2[CH:20]=[C:21]([CH:23]=[CH:24][CH:25]=2)[NH2:22])=[CH:15][N:14]=1>>[FH:1].[NH2:12][C:13]1[N:14]=[CH:15][C:16]([C:19]2[CH:20]=[C:21]([NH:22][C:2]3[CH:7]=[CH:6][C:5]([I:8])=[CH:4][C:3]=3[N+:9]([O-:11])=[O:10])[CH:23]=[CH:24][CH:25]=2)=[CH:17][N:18]=1

Participants

3

Reactant 2

HCID 145905821-Fluoro-4-iodo-2-nitrobenzeneHCID 54265176HCID 54265176, compound

Product 1

HCID 67482348HCID 67482348, compoundYield 79%

Procedure

N-(3-(2-aminopyrimid-5-yl)phenyl)-2-nitro-4-iodoaniline hydrofluoride (6l) was prepared analogously from 1c (Example 1) and 2l (Example 7). Yield: 79%. Mp 236-238° C.

Sources & evidence

ORD record
ord-997dba178cc24c5fbef92ccffa1032a4
Source dataset
uspto-grants-1999_07
Patent number
US05922724

Reaction notes

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