Furan-2-boronic acid → HCID 53811451, compound

HRID 581939Notes

Reaction equation

HRID 581939 reaction equation
F.[CH3:2][N:3]([CH3:27])[C:4]1[N:9]=[CH:8][C:7]([C:10]2[CH:11]=[C:12]([NH:16][C:17]3[CH:22]=[CH:21][C:20](I)=[CH:19][C:18]=3[N+:24]([O-:26])=[O:25])[CH:13]=[CH:14][CH:15]=2)=[CH:6][N:5]=1.[O:28]1[CH:32]=[CH:31][CH:30]=[C:29]1B(O)O>>[CH3:2][N:3]([CH3:27])[C:4]1[N:9]=[CH:8][C:7]([C:10]2[CH:11]=[C:12]([NH:16][C:17]3[CH:22]=[CH:21][C:20]([C:29]4[O:28][CH:32]=[CH:31][CH:30]=4)=[CH:19][C:18]=3[N+:24]([O-:26])=[O:25])[CH:13]=[CH:14][CH:15]=2)=[CH:6][N:5]=1

Participants

3

Reactant 2

HCID 2734357Furan-2-boronic acidHCID 86754223HCID 86754223, compound

Product 1

HCID 53811451HCID 53811451, compoundYield 89%

Procedure

N-(3-(2-(Dimethylamino)pyrimid-5-yl)phenyl)-4-(2-furanyl)-2-nitroaniline (7m) was prepared analogously from 6h (Example 10) and 2-furanylboronic acid in 89% yield. Mp 160-161° C.

Sources & evidence

ORD record
ord-634c170e31f443c29f779e4f2dc6a890
Source dataset
uspto-grants-1999_07
Patent number
US05922724

Reaction notes

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